Vaccinations had been used as 1796, when Edward Jenner created the initial vaccine to get smallpox (Alexandra). Since then, vaccines have demolished several infections such as smallpox and polio. Vaccines are not required of students going to schools till 1855, once Massachusetts unplaned a vaccination law for smallpox. By 1920, above half of the United States passed vaccination laws requiring school children to obtain a smallpox vaccination. Smallpox would afterwards..