Endocrine Disorder Summary (Addison’s disease). Name Date Introduction Addison’s disease is a disorder which develops when the adrenal glands produce inadequate hormones. It adrenocortical insufficiency which occurs due to the dysfunction of the whole adrenal cortex. It mainly affects the mineralocorticoid and glucocorticoid function. Addison’s disease onset begins when 90% or even the adrenal cortices are destroyed. This disease affects around 110-144 for every 1 million people in the industrialized nations (Hahner et al. 2010). Background Addison’s disease was first recognized in 1855 by Thomas Addison who defined it as a disorder of long-term adrenal insufficiency which is developed over a long period coupled with weight loss anorexia fatigue weakness and hyperpigmentation being the key symptoms (White & Arlt 2010). Pathophysiology Deficiency of adrenocortisol hormone typically results in reversal of the effects of key hormones such as Aldosterone and Cortisol thus producing adrenal crisis clinical findings. The very first feeling weak tired or even weight loss. When ill one must learn to elevate the amount of corticosteroid for adrenal insufficiency (Sarkar et al. 2012). A healthcare provider can be asked to write down instruction for people who are sick. People who are at risk may be required to change their diets by taking diet rich in sodium. References Hahner S. Loeffler M. Bleicken B et al. (2010). Epidemiology of adrenal crisis in chronic adrenal insufficiency: the need for new prevention strategies. European Journal of Endocrinology 162(3): 597-602 White K. & Arlt W. (2010). Adrenal crisis in treated Addison’s disease: a predictable but under- managed event. European Journal of Endocrinol 162(1): 115-120 Napier C et al. (2014). Current and Emerging Therapies for Addison’s disease. PubMed. Current Opin Endocrinol Diabetes Obes. Sarkar S. B. Sarkar S. Ghosh S. R. & Bandyopadhyay S. (2012). Addison’s disease. Contemporary Clinical Dentistry 3(4) 484-486 [...]
WRITE A SUMMARY REPORT ON ADDISON'S DISEASE, Your summary report need not be extensive or lengthy, but should combine short summaries of the following: background of the condition including a summary of its effects on public health; etiology of the condition; relevant pathophysiology; signs and symptoms; current and possible future treatments; suggestions on how recognition can be incorporated into public health practice, screening, education, and prevention. Your summary report should include cited medical and/or academic sources that support information provided.