Sickle cell disease essay

I also certify that this essay was prepared by me specifically for this course. Williams, T. N. , & Chakravorty, S. Sickle cell disease: a neglected chronic disease of increasing global health importance. Using existing research, the authors give a historical perspective of the sickle cell disease, which include the initial description of the disease, the advances in clinical treatment, the funding and research incentives, and the challenges in treating and managing sickle cell disease in spite of the improvements. Based on the article, it can be stated that the author lack a specific objective offer a rather general and historical information about sickle cell disease as a threat to human health. It is noted in the article that the origin of the disease is the malaria regions of the tropics where the carriers are protected from death from malaria and enjoy an evolutionary advantage.

The worldwide migration of the population has given the condition a global distribution and there is a substantial number of children that are born with the condition in the developed regions such as Europe and America. With the improvements in medical approaches in management and diagnosis, the life expectancy of victims has increased. The author notes that sickle cell disease is the most common inherited blood disorder in the United Kingdom. Although the condition reduces the life expectancy, it is possible to manage the symptoms and complications effectively. The condition is identified as an autosomal recessive genetic condition that results from the presence of mutated form of hemoglobin that polymerizes under low oxygen and causes the red blood cells to become sickle-shaped.

In the process, the other cells are activated through process like vasculopathies that consequently cause loss of blood supply in the tissue. Clinically, the disease manifests fast when the child reaches the age of 6-12 months. L. Sickle Cell Disease: A Continued Call to Action. American Journal of Preventive Medicine, 51(1S1), S1-S2. Retrieved from https://www. ajpmonline. As suggested in the article, there are also interventions that can be used to improve the condition of victims and increase their life expectancy. Importantly, there is a need for effective policies that will ensure that all the affected individuals, especially those from minor people groups receive adequate medical care. Therefore, Hassell’s article contributes towards the understanding of the history of sickle cell disease, the policy gaps in medical care among minor groups, and how these gaps can be sealed to ensure equality.

Adewoyin A. S. The treatment and management of this condition in regions like Nigeria are still suboptimal and there is a need to enhance the knowledge of sickle cell disease phenotypes and comprehensive care among Nigerian physicians to improve the life quality of victims. In this regard, the author provides a thorough review of the aetiopathogenesis, clinical manifestations, and management of the sickle cell disease in Nigeria, majorly focusing on the local patterns and peculiarities. Further, the paper provides treatment guidelines that are appropriate for the Nigerian setting, including recommendations for enhancing care for people affected with the condition. A close examination of the articles reveals the importance of developing and choosing treatment methods that are suitable for the settings of the victims.