Biological effects on the interactions between ultrasound and tissue

Document Type:Research Paper

Subject Area:Biology

Document 1

Ultrasound generates high-frequency vibrational waves which penetrate through the body’s soft tissues. Once in the tissues the waves scatter and reflect from different tissues they came in contact with during traveling. The basis of any therapeutic applications is the thermal and non-thermal effects and biological effects of the procedure on tissues. The technology of focused ultrasound leads to a broad biological impact on the tissue which enables the treatment of many clinical conditions. How a biological tissue responds to ultrasound depends on many factors. The magnitude and long it lasts will depend on the “thermal dose” the tissue was given. The energy produced by the ultrasound could lead to a low thermal rise or some minutes or probably hours. The energy generated by the ultrasound could be high levels of temperature s that lasts for a short time and will destroy the tissue.

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Biological effects The focused ultrasound can produce up to seventeen diverse biological effects due to the interaction with tissue. These effects enhance the treatment of various diseases. The bubbles used in inertia cavitation are very visible thus enhancing accurate targeting. b) Target drug delivery Ultrasound has been used to deliver drugs to various targeted parts of the body. Sonoporation Cell membranes are known to hinder large bodies from moving to the cells. An example could be genes and drugs. The mechanical force of focused ultrasound makes the cell membrane permeable allowing the absorption of drugs through a process called sonoporation. This happens when oxygen and blood transportation is increased. It also improves treatment by expanding the delivery of drugs to particular areas.

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