Tuberculosis pathogenic analysis

Document Type:Thesis

Subject Area:Biology

Document 1

Tuberculosis (TB) is an infectious disease contributing to high mortality rate in the world. Tuberculosis is a bacterial pathogenic disease that can be chronic and severe if not treated. The bacteria are spread from one person to another through the air. The bacteria are spread through coughing, speaking of even singing. There are two types of TB, namely latent tuberculosis infection and the tuberculosis disease. The victim also experiences pain in the chest and coughing out sputum or blood. The victim also demonstrates other sign like loss of weight, lack of appetite, experience sweating during cold nights, and high body fever (Blekhman et al. These sign starts to develop after latent TB develops into TB diseases. Lack of seeking urgent medical attention allows devolving of the bacteria and more weakening of the immune system.

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Mycobacterium tuberculosis is the main culprit the most infectious disease TB. The cord factor is poisonous to the cell of humans. The cord factor is produced during the virulent strains of the bacteria. The pathogenesis of TB starts with the dispersion of TB aerosols. After the distribution in the air, it creates the risk of conducting the disease. Infection occurs when one inhales a droplet of the aerosols containing the bacteria and reaches the alveoli. Diagnosis is a crucial step before treatment. Blood tests and skin tests remain common diagnostic ways for TB. Skin test diagnosis is made by injecting of PPD tuberculin below the skin, and swelling suggests infection from TB. The doctor also administers a physical examination. Sputum tests using x-ray are used to test TB.

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