Keywords: gc applications in pharmaceutical analysis Chromatography is a physical approach to separation in which components to be segregated are allocated between two stages, one of which is stationary stage as the other mobile period move in a particular direction. The fixed phase may be considered a solid or a liquid recognized on a solid or a gel. The mobile phase may be gaseous or liquid. The basis for gas chromatography parting is the circulation of a sample between two stages. one of these stages is a stationary bed of large surface area, and the other phase is a gas which percolates through the stationary foundation. The physical point out of the mobile phase distinguishes the essential kind of a chromatographic parting.