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In order to understand Lambert-Eaton Syndrome (LES), then it's first essential to have an overall understanding of the nervous system. The human nervous system is composed of the central nervous system (CNS), which comprises the brain and spinal cord, and the peripheral nervous system (PNS), that includes all of the neural tissue away from the CNS. PNS is composed of two standard kinds of neurons (nerve cells): motor nerves and sensory neurons. Motor volunteers, the target of LES, are used to send signals in the CNS into the human body to arouse a reaction. The most important of these reactions when talking LES are muscle contractions. Sensory neurons move information another way, by the PNS to the CNS, and bring info regarding the environment to the brain. The nerve itself consists of a cell body (called a soma), an axon, and dendrites. Nerves send signals employing an electric charge that is passed out of the dendrites,into the axon, then into the next cell. This electric signal, known as a nerve impulse, is generated by the motion of ions. Sodium (Na+) ions migrate in the nerve cell due to stimulation from the central nervous system. This creates a web localized positive charge inside the cell, called an action potential. However, the positive cost degrades as it goes through the cell since the ions may diffuse (and then so will the local cost). The neural cell has invented a mechanism to maintain the magnitude of the control it receives after which afterwards transmits at a constant price. There are a set of nodes across the axon in which there is a high concentration of sodium (Na+) and K+ channels. There is a high concentration of Na+ outside the cell and also a higher concentration of K+ within the cell. Since the nodes sen.. .