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Many researchers study the adverse effects following substance use in young adolescents using co-occurring mood and anxiety disorders, however exactly what would be the results in older adolescents and young adults that are attending youth drug therapy services? In a study by Lubman, Allen, Rogers, Cementon, and Bonomo, conducted between 2004 and 2005, young people were interviewed regarding their drug use, psychopathology, risk-taking behaviors, and high quality of life. The researchers tried to find whether childhood with depressive and anxiety disorders had higher rates of psychological dependence and exhibit a greater degree of poly drug use. Also, the investigators aimed to show whether youth with mental and anxiety disorders would have more substance-related problems, health risk behaviors, and a poorer quality of life. The study had only one hundred topics whose age ranged from 16 to 22. The participants were chosen from two urban youth drug treatment providers in Melbourne, Australia. Each participant has been interviewed about their drug use, psychopathology, risk-taking behaviours, and high quality of life. Also the participants had been asked to complete self-report rating scales which included variables such as amount of psychological distress, degree of harmful drinking, degree of emotional dependence in their drug of choice, frequency of substance use within the previous month, and objects measuring the participantsвЂ™ quality of lifestyle. The investigators found that participants who have significant depressive disease and participants with post-traumatic stress disorder (PTSD) had higher psychological health and substance use comorbidity than people that suffered from substance use problems alone. This paper will examine the study by Lubman et.