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Transmission of the Plague to Human beings Abstract Yersinia pestis is definitely a bacterium that is popular to mankind for years and years. Its mechanisms of survival in wide selection of species are extraordinary. The energy of this bacterium would depend on its manipulation of the disease fighting capability of its host’s. Its method of survival in the flea and its own usage of the flea as a vector to additional desired hosts portray this bacterium’s true capacity. This flea is the primary reason behind the bacterium to additional animals, humans especially. However, the bacterium does not stop here; it uses its coded proteins to inhibit the host’s disease fighting capability and the host’s cellular functions to assist in its survival in the organism. Probably the most deadly illnesses to strike mankind may be the plague. The plague offers survived for years and years and has claimed the entire lives of millions through the entire years. The plague is the effect of a gram-negative bacterium referred to as Yersinia pestis. There were three major pandemics because of this bacterium. Although it does not appear as deadly now as it was in the Middle Ages, it is extremely much alive and present still. There are three types of plague: the bubonic, pneumonic and septicemic plague. The septicimic and bubonic plague are just transmitted by the flea, however the pneumonic plague can spread through the air in droplets or by physical contact. At times, transmission may also occur from infected rodents, cats or other animals through bites and scratches (Phillips, 2004). The bacteria’s essential for survival is based on its vast selection of hosts. Its system in manipulating the host’s cellular features has allowed it to assume control and survive over time. However, the procedure that the bacteria must proceed through to be able to infect a human being relie...