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Table 1: Literature search details Databases Searched Keywords and MeSH Headings Amount of Hits Number of related content PubMed NCBI Osteopathy, arthritis, knee 8801 50 PubMed NCBI CAM, knee, osteopathy 342 35 PubMed NCBI Acupuncture, arthritis, knee 310 12 PubMed NCBI Randomized controlled trial, knee, osteoarthritis, acupuncture 141 10 As a weight-bearing joint, your knee can develop atherosclerosis over time because of "wear and tear". This happens when the knee's joint cartilage illuminates and the bone below begins to deteriorate, resulting in pain, stiffness, swelling and compromised function of this joint. Osteoarthritis is the most common sort of knee arthritis also affects largely the middle-aged and the elderly (Srikulmontree 2012). To alleviate symptoms, patients can resort to a variety of treatments such as exercise, drug therapy, surgery and alternative techniques such as acupuncture. Laughter is a complementary or alternative medicine arising from early China. It comprises the insertion of needles to certain pressure points of the human body. It's believed to be a remedy for a variety of conditions, particularly those associated with noticeable pain, like knee osteoarthritis (OA). But, though acupuncture was used for thousands of years (White and Ernest 2004) that the effectiveness of this treatment method hasn't been established. This important literature review will compare two published papers that explore the impact that it has on individuals with osteoarthritic knees. Paper 1 Tukmachi et al (2004) investigated utilizing the effectiveness of acupuncture both independently and as an adjunctive treatment for knee arthritis working with a open air control trial. Adult patients having a history of more than si...