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The dental anxiety and anxiety is an emotional distress illness that can lead to bad dental health in children, adolescents and adults. Researches of several studies investigated the source, influence factors, physiological and physical reactions, and kinds of management and intervention for dental phobia through different sources. Qualitative study utilized YouTube to get insight into the general public's view of dental fear and anxiety and comprehend the psychological effect in children and teens. Studies from collective literature research through EBSCOhost, Medline, PsycINFO, and Google Scholar databases revealed methods of intervention to help reduce dental anxiety and the avoidance of dental therapies. And a pharmacological study on 5-HT 3 antagonist can guide the way to discover a better anxiolytic that can potentially obstruct the anxiogentic effects in individuals with anxiety disorder and social anxiety including dental fear and stress. The Studies of Dental Stress and Anxiety in Children, Adolescents, and Adults Generally, when folks experience psychological distress such as fear from some circumstances our bodies will trigger the fight or flight response to cope with the specific hazard (Gordon, Heimberg, Tellez, and Ismail, 2013). It's probable that after those feelings were introduced to people, we then produced a sense of stress for possible future threat. As Gordon, Heimberg, Tellez, and Ismail (2013) had demonstrated that this sense of anticipation is what caused the conditioned reaction in our bodies known as stress, the notion of phobia could be arrange in various levels of seriousness. A closer look of dental fear and anxiety (DFA) research in children and adolescents revealed that anxiety disorder could improved early in life.