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Down Syndrome Chromosome Rogue One Down syndrome affects one out of 700 children born in the United States. A chromosomal disorder connected with all the twenty first chromosome group, brings a lifetime of challenges to the affected person. Down syndrome is related to intellectual disability, a characteristic facial appearance and diminished muscle tone throughout infancy according to Genetics Home Reference (2013). There are three different situations in which Down syndrome can happen. Down syndrome typically occurs as the result of getting an additional twenty initial chromosome. This additional twenty first chromosome can be seen from the image to the left. This additional chromosome in the cell happens as a mistake that takes place during cell division between the female's egg cell and the male's sperm cell. This error in cell division, called nondisjunction, is that the reason for 95 percent of Down syndrome births. This is also known as Trisomy 21. Another cause of Down syndrome is when the cells have the proper amount of chromosomes to begin with after fertilization, but when the cells are rapidly dividing one or more of these cells may end up with an excess chromosome twenty-one. This way of getting down syndrome, called cell line mosaicism is infrequent, and the person shows less severe signs of the normal Down syndrome disorder. The third situation of Down syndrome can also be uncommon and is caused by using the normal number of chromosomes but a whole chromosome twenty individual being attached to another set of chromosomes. This is known as Robertsonian translocation and happens in about three to four per cent of Down's syndrome cases. The disorder of Down syndrome is not found within a specific gender or race. Down syndrome is nevertheless found equally between a.. .