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History of Down's Syndrome Essay

Project id 1000714
Subject area Biology
Document type Essay
Words 3441
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Down’s Syndrome is known as after John Langdon Straight down, a British doctor who first studied and explained the mental disorder. The disorder was uncovered by him in Surrey, England while working at an asylum for children with mental retardation. He known as people who have this disorder Mongoloids due to the physical similarities of residents from Mongolia in comparison to those suffering from Down’s Syndrome. Later, the word “Mongoloid” was dropped and called after John Straight down when Jerome Lejeune, a French geneticist who tested kids with these equivalent physical features of Mongolians, discovered that 97% of these tested had a supplementary chromosome-21, with a complete of 47 chromosomes. Down’s Syndrome is certainly a common disorder because of a supplementary chromosome number; it really is the most typical reason behind mental retardation occurring in 1 in 1,000 babies in the usa. (Genetic Science Learning Middle) There are three types of Down’s Syndrome: Trisomy 21, Translocation, and Mosaicism. Trisomy 21 is the most typical kind of Down’s Syndrome; it happens in 95 percent of Down’s Syndrome situations. Trisomy 21 is a problem when a newborn receives a supplementary third chromosome-21, of the standard 2 instead. The second kind of Down’s Syndrome is Translocation; it occurs when just a little little bit of the chromosome-21 is available on another chromosome. Just 3 percent of these with Down’s Syndrome have problems with Translocation. Mosaicism may be the third kind of Down’s Syndrome as well as the rarest; it is a problem where newborns have a variety of cells in the chromosome-47 which has a supplementary chromosome-21. Only 2 percent of individuals with Down’s Syndrome have Mosaicism. (Hauser-Cram, 15) Factors behind Down’s Syndrome remain unknown. There is absolutely no real way to avoid the occurrence of Straight down’s Syndrome,...

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