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There are many different diseases, disorders, and adjustments of the musculoskeletal system and the integumentary system. Each disease differs. Tissue changes, transports, treatments, preventative measures all vary between the diseases, infections, as well as systems. "Muscular dystrophies are a group of bronchial ailments that cause degeneration of skeletal muscle fibers" (Huether, McCance, 2010, pp. 1633). There are multiple muscle diseases but muscle dystrophies are the most common in kids. There are at least three specific kinds of muscular dystrophies which are genetically different; limb girdle, Duchenne, and oculopharyngeal. Each case of muscular dystrophy is "Characterized by progressive, symmetric weakness and wasting of muscle groups, together with increasing disability and deformity" (Huether, McCance, 2010, pp. 1633). The progressive pathophysiology of muscle dystrophy in muscle cell chemistry, membrane transport, and connective tissue changes varies over every type. Muscular dystrophies have a progressive pathophysiology that is explained in five distinct phases. Stage 1 is known as presymptomatic which means that the individual has family history of a muscle dystrophy. Stage 2 is called premature ambulatory which means the child has developed extremity weakness, can walk on toes, Gowers sign, and muscular weakness. Stage 3 is known as late ambulatory which is an increased difficulty in walking, lack of respiratory muscle strength, and forced vital capacity which ends in nocturnal hypoxemia. Stage 4 is called early nonambulatory that's when the individual can maintain his or her posture and it's also the possibility of growth of scoliosis. Stage 5 is called late nonambulatory that is the possi...